MANTA

We've developed an R package for Microbial Assemblage Normalized Transcript Analysis [MANTA] to perform comparative metatranscriptomics. The software accepts count or alignment data as input, provides cross tabulation routines, facilitates normalization and significance estimation and outputs summary tables and publication quality differential expression plots as well as visual and statistical quality control diagnostics.

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Additional Resources

EdgeR Bioconductor page
EdgeR Bioinformatics paper
More information on RA plots

Referencing Articles

PNAS 18 January 2012 "Comparative metatranscriptomics identifies molecular bases for the physiological responses of phytoplankton to varying iron availability".