Sacha Coesel

Research Scientist

coesel at uw.edu

Education

  • 2008 - PhD in Molecular Biolology, University of Algarve (Portugal), partly hosted by the Stazione Zoologica ‘Anton Dohrn’ (Italy). Thesis advisors: Prof. Dr. Joao Varela (UALG) and Prof. Dr. Chris Bowler (SZN). Thesis title: Regulation of the carotenoid biosynthetic pathway in the green microalga Dunaliella salina and the diatom Phaeodactylum tricornutum.
  • 1999 - BS in Biotechnology, Noordelijke Hogeschool Leeuwarden (Netherlands).
  • Positions held

  • Research scientist, School of Oceanography, University of Washington (USA), 2016-Present 
  • Postdoctoral research fellow, Institute for Systems Biology (USA), 2015-2016
  • Postdoctoral research fellow, Institute for Systems Biology (USA), 2008
  • Graduate research assistant, Stazione Zoologica ‘Anton Dohrn’ (Italy), 2004-2008
  • Graduate research assistant, Centre of Marine Sciences, University of Algarve (Portugal), 2001-2004
  • Research technician, Centre of Marine Sciences, University of Algarve (Portugal), 1999-2001
  • Undergraduate research assistant, Centre of Marine Sciences, University of Algarve (Portugal), 1999
  • Undergraduate research assistant, Faculty of Sciences, Vrije Universiteit Amsterdam (Netherlands), 1998
  • Publications

  • Ashworth J, Coesel S, Lee A, Armbrust EV, Orellana M, Baliga NS (2013) Diurnal growth state transitions in the diatom Thalassiosira pseudonana. PNAS 110 (18): 7518–23
  • Bailleul B, Rogato A, de Martino A, Coesel S, Cardol P, Bowler C, Falciatore A, Finazzi G. (2010) An atypical member of the light-harvesting complex stress-related protein family modulates diatom responses to light. PNAS, 107(42):18214-9
  • Coesel S, Mangogna M, Ishikawa T, Heijde M, Rogato A, Finazzi G, Todo T, Bowler C, Falciatore A. (2009) Diatom PtCPF1 is a new cryptochrome/photolyase family member with DNA repair and transcription regulation activity. EMBO Reports, 10(6):655-61
  • Coesel S, Oborník M, Varela J, Falciatore A, Bowler C. (2008) Evolutionary origins and functions of the carotenoid biosynthetic pathway in marine diatoms. PLoS One, 3(8):e2896
  • Bowler C, Allen AE, Badger JH, Grimwood J, Jabbari K, Kuo A, Maheswari U, Martens C, Maumus F, Otillar RP, Rayko E, Salamov A, Vandepoele K, Beszteri B, Gruber A, Heijde M, Katinka M, Mock T, Valentin K, Verret F, Berges JA, Brownlee C, Cadoret JP, Chiovitti A, Choi CJ, Coesel S, De Martino A, Detter JC, Durkin C, Falciatore A, Fournet J, Haruta M, Huysman MJ, Jenkins BD, Jiroutova K, Jorgensen RE, Joubert Y, Kaplan A, Kröger N, Kroth PG, La Roche J, Lindquist E, Lommer M, Martin-Jézéquel V, Lopez PJ, Lucas S, Mangogna M, McGinnis K, Medlin LK, Montsant A, Oudot-Le Secq MP, Napoli C, Obornik M, Parker MS, Petit JL, Porcel BM, Poulsen N, Robison M, Rychlewski L, Rynearson TA, Schmutz J, Shapiro H, Siaut M, Stanley M, Sussman MR, Taylor AR, Vardi A, von Dassow P, Vyverman W, Willis A, Wyrwicz LS, Rokhsar DS, Weissenbach J, Armbrust EV, Green BR, Van de Peer Y, Grigoriev IV (2008) The Phaeodactylum genome reveals the evolutionary history of diatom genomes. Nature, 456(7219):239-44
  • Coesel S, Baumgartner A, Teles L, Ramos A, Henriques N, Cancela L, Varela J. (2008) Nutrient limitation is the main regulatory factor for carotenoid accumulation and for Psy and Pds steady state transcript levels in Dunaliella salina (Chlorophyta) exposed to high light and salt stress. Marine Biotechnology (NY), 10(5):602-11
  • Ramos A, Coesel S, Marques A, Rodrigues M, Baumgartner A, Noronha J, Rauter A, Brenig B, Varela J. (2008) Isolation and characterization of a stress-inducible Dunaliella salina Lcy-beta gene encoding a functional lycopene beta-cyclase. Applied Microbiology and Biotechnology, 79(5):819-28
  • Montsant A, Allen AE, Coesel S, de Martino A, Falciatore A, Heijde M, Jabbari K, Maheswari U, Mangogna M, Rayko E, Siaut M, Vardi A, Apt K, Berges J, Chiovitti A, Davis A, Hadi M, Lane T, Lippmeier, Martinez D, Parker M, Pazour G, Saito M, Thamatrakoln K, Rokhsar D, Armbrust EV, Bowler C (2007) Identification and comparative genomic analysis of signaling and regulatory components in the diatom Thalassiosira pseudonana. Journal of Phycology, 43: 585-604
  • Siaut M, Heijde M, Mangogna M, Montsant A, Coesel S, Allen AE, Manfredonia A, Falciatore A, Bowler C. (2007) Molecular toolbox for studying diatom biology in the diatom Phaeodactylum tricornutum. Gene,406:23-35